Environmental mutagenesis

Laboratory of Environmental Mutagenesis: Summary Statement

The primary objective of the Institute's program in mutagenesis is focused on evaluation and definition of risks to both human somatic and germinal tissue resulting from exposure to genetically active environmental chemicals. The Laboratory of Environmental Mutagenesis was organized late in FY 1972. Because of the worldwide shortage of resources for the rapid development of research in various ...

Mutation research, genetic toxicology and environmental mutagenesis.

ING AND INDEXING

The role of repair in environmental mutagenesis.

Pollen tetrads in the detection of environmental mutagenesis.

Although pollen viability promises to be a very sensitive indicator of environmental mutagenesis, its utility in this regard is confounded by the fact that it is influenced also by nonmutagenic environmental stress. However, with appropriately homozygous material, we may discriminate between mutagenic and nonmutagenic influences on pollen viability. Pollen inviability resulting from mutagenesis...

Goals and programs of the laboratory of environmental mutagenesis.

In the formation of the programs for such a laboratory, it is important to set some goals and then to ask the question, "How can these goals be achieved?" The societal goal for the LEM is the prevention of increased frequency of genetic disease in the human population. That goal covers the waterfront, however, and the LEM cannot possibly cover all the scientific areas necessary to accomplish th...